7wq4: Difference between revisions
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==== | ==Galanin-bound galanin receptor 2 in complex with Gq== | ||
<StructureSection load='7wq4' size='340' side='right'caption='[[7wq4]]' scene=''> | <StructureSection load='7wq4' size='340' side='right'caption='[[7wq4]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7wq4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Rattus Rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WQ4 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wq4 OCA], [https://pdbe.org/7wq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wq4 RCSB], [https://www.ebi.ac.uk/pdbsum/7wq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wq4 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wq4 OCA], [https://pdbe.org/7wq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wq4 RCSB], [https://www.ebi.ac.uk/pdbsum/7wq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wq4 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/GALR2_HUMAN GALR2_HUMAN] Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).<ref>PMID:24517231</ref> <ref>PMID:25691535</ref> <ref>PMID:9480833</ref> <ref>PMID:9685625</ref> <ref>PMID:9832121</ref> <ref>PMID:9880084</ref> | |||
==See Also== | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bos taurus]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus]] | ||
[[Category: Duan J]] | |||
[[Category: Jiang Y]] | |||
[[Category: Shen DD]] | |||
[[Category: Xu HE]] | |||
[[Category: Zhang Y]] | |||
