BASIL2022GV3HDT: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 36: | Line 36: | ||
== Docking== | == Docking== | ||
This <scene name='90/904996/Binding_pockets/1'>potential binding pocket</scene> is an area where the substrate dCMP may bind on 3HDT. Also, it was an area that dCMP binded to with the most affinity in PyRx. The amino acids interacting with the substrate are.... | This <scene name='90/904996/Binding_pockets/1'>potential binding pocket</scene> is an area where the substrate dCMP may bind on 3HDT. Also, it was an area that dCMP binded to with the most affinity in PyRx. The amino acids interacting with the substrate are.... | ||
[[Image:Possible binding pockets.png | 300px| center | thumb| Predicted binding pockets for 3HDT represented by the white shperes ]] | |||
[[Image:DCMP.png | 300px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink) ]] | |||
[[Image:DCMP reaction.png |300px| center|thumb | Binding affinity was increased when hydroxyl group removed from ribose ring on CMP to make dCMP]] | |||
== Laboratory Experiments == | == Laboratory Experiments == | ||
