BASIL2022GV3HDT: Difference between revisions
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==Characterizing Putative Kinase 3HDT== | ==Characterizing Putative Kinase 3HDT== | ||
<StructureSection load=' | <StructureSection load='3hdt.pdb' size='340' side='right' caption='Structure of putative kinase 3HDT' scene='90/904996/3hdt_structure_1st_pic_on_pg/3'> | ||
Putative kinase (3HDT) shows limited activity as a cytidylate kinase, utilizing ATP and dCMP as ligands. | Putative kinase (3HDT) shows limited activity as a cytidylate kinase, utilizing ATP and dCMP as ligands. | ||
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[[Image:POCASA 3hdt image 2.png | 500px| center | thumb| Predicted binding pockets for 3HDT represented by the white stippling.]] | [[Image:POCASA 3hdt image 2.png | 500px| center | thumb| Predicted binding pockets for 3HDT represented by the white stippling.]] | ||
Some of the predicted | Some of the predicted bind pockets were areas where ATP (red arrow) and dCMP (yellow arrow) binded to with the highest affinity in PyRx. | ||
[[Image:DCMP.png | 400px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink) ]] | [[Image:DCMP.png | 400px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink) ]] | ||
