2y0n: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
Line 3: Line 3:
<StructureSection load='2y0n' size='340' side='right'caption='[[2y0n]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2y0n' size='340' side='right'caption='[[2y0n]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2y0n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y0N FirstGlance]. <br>
<table><tr><td colspan='2'>[[2y0n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y0N FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0n OCA], [https://pdbe.org/2y0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y0n RCSB], [https://www.ebi.ac.uk/pdbsum/2y0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0n ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0n OCA], [https://pdbe.org/2y0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y0n RCSB], [https://www.ebi.ac.uk/pdbsum/2y0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MS3L1_HUMAN MS3L1_HUMAN]] May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.<ref>PMID:16227571</ref> <ref>PMID:20018852</ref> <ref>PMID:20657587</ref> <ref>PMID:20943666</ref>
[https://www.uniprot.org/uniprot/MS3L1_HUMAN MS3L1_HUMAN] May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.<ref>PMID:16227571</ref> <ref>PMID:20018852</ref> <ref>PMID:20657587</ref> <ref>PMID:20943666</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Akhtar, A]]
[[Category: Akhtar A]]
[[Category: Cusack, S]]
[[Category: Cusack S]]
[[Category: Hallacli, E]]
[[Category: Hallacli E]]
[[Category: Holz, H]]
[[Category: Holz H]]
[[Category: Kadlec, J]]
[[Category: Kadlec J]]
[[Category: Lipp, M]]
[[Category: Lipp M]]
[[Category: Weatherby, J Sanchez]]
[[Category: Sanchez Weatherby J]]
[[Category: Chromatin]]
[[Category: Msl complex]]
[[Category: Transcription]]
[[Category: X chromosome]]