Syncytin: Difference between revisions
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<b> Alzheimer's Disease </b> | <b> Alzheimer's Disease </b> | ||
An abnormal influx of calcium has been linked to the development of Alzheimer’s Disease in individuals. Overexpression of syncytin-1 has been linked to the influx of calcium ions in neuroblastoma cells. Along with the influx of calcium, nitric oxide also contributes to the development of Alzheimer’s Disease as it regulates the inflammatory response of the brain and neuronal cells <ref name='fossils'/>. An increase in syncytin-1 levels has the capability to activate the enzyme nitric oxide synthase | An abnormal influx of calcium has been linked to the development of Alzheimer’s Disease in individuals. Overexpression of syncytin-1 has been linked to the influx of calcium ions in neuroblastoma cells. Along with the influx of calcium, nitric oxide also contributes to the development of Alzheimer’s Disease as it regulates the inflammatory response of the brain and neuronal cells <ref name='fossils'/>. An increase in syncytin-1 levels has the capability to activate the enzyme nitric oxide synthase in astrocytes which then induces the release of the redox reaction product, nitric oxide. These, in turn, are cytotoxic to oligodendrocytes which can damage axons <ref name='ncbifrontiers'/>. | ||
<b> Cancer </b> | <b> Cancer </b> | ||