GLUT1: Difference between revisions
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===Retina=== | ===Retina=== | ||
GLUT1 is the most abundant glucose transporter in the retina. Retinal pigmented epithelium and retinal capillary endothelium, the tissues that comprise the retina-brain barrier, express GLUT1.<ref>PMID:33916246</ref> The retina has a consistently high energy requirement due to abundance of energy-consuming enzymes such as [[Sodium-Potassium ATPase]]. Studies on mice have shown that GLUT1 knockout leads to photoreceptor cell death | GLUT1 is the most abundant glucose transporter in the retina. Retinal pigmented epithelium and retinal capillary endothelium, the tissues that comprise the retina-brain barrier, express GLUT1.<ref>PMID:33916246</ref> The retina has a consistently high energy requirement due to abundance of energy-consuming enzymes such as [[Sodium-Potassium ATPase]]. Studies on mice have shown that GLUT1 knockout leads to photoreceptor cell death - a greater effect was noted in rod cells versus cone cells.<ref>PMID:30462537</ref> | ||
== Disease == | == Disease == | ||
