7xn1: Difference between revisions

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'''Unreleased structure'''


The entry 7xn1 is ON HOLD
==Crystal structure of human acetylcholinesterase in complex with tacrine==
 
<StructureSection load='7xn1' size='340' side='right'caption='[[7xn1]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
Authors: Dileep, K.V., Ihara, K., Mishima-Tsumagari, C., Kukimoto-Niino, M., Yonemochi, M., Hanada, K., Shirouzu, M., Zhang, K.Y.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7xn1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=7e3i 7e3i]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XN1 FirstGlance]. <br>
Description: Crystal structure of human acetylcholinesterase in complex with tacrine
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene>, <scene name='pdbligand=THA:TACRINE'>THA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xn1 OCA], [https://pdbe.org/7xn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xn1 RCSB], [https://www.ebi.ac.uk/pdbsum/7xn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xn1 ProSAT]</span></td></tr>
[[Category: Hanada, K]]
</table>
[[Category: Yonemochi, M]]
== Function ==
[[Category: Kukimoto-Niino, M]]
[https://www.uniprot.org/uniprot/ACES_HUMAN ACES_HUMAN] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.<ref>PMID:2714437</ref> <ref>PMID:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref>
[[Category: Ihara, K]]
== References ==
[[Category: Zhang, K.Y.J]]
<references/>
[[Category: Shirouzu, M]]
__TOC__
[[Category: Mishima-Tsumagari, C]]
</StructureSection>
[[Category: Dileep, K.V]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Dileep KV]]
[[Category: Hanada K]]
[[Category: Ihara K]]
[[Category: Kukimoto-Niino M]]
[[Category: Mishima-Tsumagari C]]
[[Category: Shirouzu M]]
[[Category: Yonemochi M]]
[[Category: Zhang KYJ]]
Retrieved from "https://proteopedia.org/7xn1"