1h57: Difference between revisions

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[[Image:1h57.jpg|left|200px]]
{{Seed}}
[[Image:1h57.png|left|200px]]


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{{STRUCTURE_1h57|  PDB=1h57  |  SCENE=  }}  
{{STRUCTURE_1h57|  PDB=1h57  |  SCENE=  }}  


'''STRUCTURE OF HORSERADISH PEROXIDASE C1A COMPOUND III'''
===STRUCTURE OF HORSERADISH PEROXIDASE C1A COMPOUND III===




==Overview==
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A molecular description of oxygen and peroxide activation in biological systems is difficult, because electrons liberated during X-ray data collection reduce the active centres of redox enzymes catalysing these reactions. Here we describe an effective strategy to obtain crystal structures for high-valency redox intermediates and present a three-dimensional movie of the X-ray-driven catalytic reduction of a bound dioxygen species in horseradish peroxidase (HRP). We also describe separate experiments in which high-resolution structures could be obtained for all five oxidation states of HRP, showing such structures with preserved redox states for the first time.
The line below this paragraph, {{ABSTRACT_PUBMED_12024218}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 12024218 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12024218}}


==About this Structure==
==About this Structure==
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[[Category: Oxyperoxidase]]
[[Category: Oxyperoxidase]]
[[Category: Peroxidase]]
[[Category: Peroxidase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:26:47 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:38:37 2008''
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