3oun: Difference between revisions

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<StructureSection load='3oun' size='340' side='right'caption='[[3oun]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
<StructureSection load='3oun' size='340' side='right'caption='[[3oun]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3oun]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OUN FirstGlance]. <br>
<table><tr><td colspan='2'>[[3oun]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OUN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.705&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3otv|3otv]], [[3ouk|3ouk]], [[3uqc|3uqc]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0020c, TB39.8 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU]), MT4029, Rv3910 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oun OCA], [https://pdbe.org/3oun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oun RCSB], [https://www.ebi.ac.uk/pdbsum/3oun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oun ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oun OCA], [https://pdbe.org/3oun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oun RCSB], [https://www.ebi.ac.uk/pdbsum/3oun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oun ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FHAA_MYCTU FHAA_MYCTU]] Regulates cell growth and peptidoglycan synthesis by binding to MviN. May inhibit the late stages of peptidoglycan synthesis.<ref>PMID:22275220</ref> [[https://www.uniprot.org/uniprot/MVIN_MYCTO MVIN_MYCTO]] Essential for cell growth and peptidoglycan synthesis.
[https://www.uniprot.org/uniprot/FHAA_MYCTU FHAA_MYCTU] Regulates cell growth and peptidoglycan synthesis by binding to MviN. May inhibit the late stages of peptidoglycan synthesis.<ref>PMID:22275220</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Alber, T]]
[[Category: Alber T]]
[[Category: Gee, C L]]
[[Category: Gee CL]]
[[Category: Fha domain]]
[[Category: Membrane associated intracellular]]
[[Category: Peptidoglycan]]
[[Category: Phosphorylation]]
[[Category: Protein binding-transferase complex]]
[[Category: Pseudokinase]]
[[Category: Regulation]]
[[Category: Ser/thr kinase]]