7t1b: Difference between revisions
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==== | ==Rev1 Ternary Complex with rCTP and Ca2+== | ||
<StructureSection load='7t1b' size='340' side='right'caption='[[7t1b]]' scene=''> | <StructureSection load='7t1b' size='340' side='right'caption='[[7t1b]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7t1b]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T1B FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t1b OCA], [https://pdbe.org/7t1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t1b RCSB], [https://www.ebi.ac.uk/pdbsum/7t1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t1b ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t1b OCA], [https://pdbe.org/7t1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t1b RCSB], [https://www.ebi.ac.uk/pdbsum/7t1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t1b ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/REV1_YEAST REV1_YEAST] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.<ref>PMID:8751446</ref> <ref>PMID:11316789</ref> <ref>PMID:16452144</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Synthetic construct]] | |||
[[Category: Freudenthal BD]] | |||
[[Category: Weaver TM]] | |||
Latest revision as of 16:57, 18 October 2023
Rev1 Ternary Complex with rCTP and Ca2+
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