7sps: Difference between revisions
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<StructureSection load='7sps' size='340' side='right'caption='[[7sps]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='7sps' size='340' side='right'caption='[[7sps]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7sps]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SPS FirstGlance]. <br> | <table><tr><td colspan='2'>[[7sps]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SPS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A0E:methyl+N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate'>A0E</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A0E:methyl+N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate'>A0E</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sps OCA], [https://pdbe.org/7sps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sps RCSB], [https://www.ebi.ac.uk/pdbsum/7sps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sps ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sps OCA], [https://pdbe.org/7sps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sps RCSB], [https://www.ebi.ac.uk/pdbsum/7sps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sps ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/GTR3_HUMAN GTR3_HUMAN] Huntington disease. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/GTR3_HUMAN GTR3_HUMAN] Facilitative glucose transporter. Probably a neuronal glucose transporter. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Jiang | [[Category: Jiang X]] | ||
[[Category: Wang | [[Category: Wang N]] | ||
[[Category: Yan | [[Category: Yan N]] | ||
Latest revision as of 16:54, 18 October 2023
Crystal structure of human glucose transporter GLUT3 bound with exofacial inhibitor SA47
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