3pxg: Difference between revisions

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<StructureSection load='3pxg' size='340' side='right'caption='[[3pxg]], [[Resolution|resolution]] 3.65&Aring;' scene=''>
<StructureSection load='3pxg' size='340' side='right'caption='[[3pxg]], [[Resolution|resolution]] 3.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pxg]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PXG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pxg]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PXG FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2y1q|2y1q]], [[2y1r|2y1r]], [[3pxi|3pxi]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.654&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxg OCA], [https://pdbe.org/3pxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pxg RCSB], [https://www.ebi.ac.uk/pdbsum/3pxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pxg OCA], [https://pdbe.org/3pxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pxg RCSB], [https://www.ebi.ac.uk/pdbsum/3pxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pxg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref> [[https://www.uniprot.org/uniprot/CLPC_BACSU CLPC_BACSU]] Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK.
[https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mei, Z Q]]
[[Category: Mei ZQ]]
[[Category: Shi, Y G]]
[[Category: Shi YG]]
[[Category: Wang, F]]
[[Category: Wang F]]
[[Category: Wang, J W]]
[[Category: Wang JW]]
[[Category: Aaa+ protein]]
[[Category: Clpb]]
[[Category: Clpc]]
[[Category: Clpx]]
[[Category: Hsp100/clp]]
[[Category: Protein binding]]
[[Category: Proteolysis]]
Retrieved from "https://proteopedia.org/3pxg"