3q62: Difference between revisions

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<StructureSection load='3q62' size='340' side='right'caption='[[3q62]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='3q62' size='340' side='right'caption='[[3q62]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3q62]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q62 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3q62]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q62 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabA, YPTB1450 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q62 OCA], [https://pdbe.org/3q62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q62 RCSB], [https://www.ebi.ac.uk/pdbsum/3q62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q62 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q62 OCA], [https://pdbe.org/3q62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q62 RCSB], [https://www.ebi.ac.uk/pdbsum/3q62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q62 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FABA_YERPS FABA_YERPS]] Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).  
[https://www.uniprot.org/uniprot/FABA_YERPS FABA_YERPS] Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Yersinia pestis co92]]
[[Category: Yersinia pestis CO92]]
[[Category: Anderson, W F]]
[[Category: Anderson WF]]
[[Category: Structural genomic]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A]]
[[Category: Kwon K]]
[[Category: Kwon, K]]
[[Category: Maltseva N]]
[[Category: Maltseva, N]]
[[Category: Zhang R]]
[[Category: Zhang, R]]
[[Category: Alpha-beta fold]]
[[Category: Csgid]]
[[Category: Hotdog fold]]
[[Category: Lyase]]

Latest revision as of 11:34, 14 March 2024

Crystal Structure of 3-hydroxydecanoyl-(acyl carrier protein) dehydratase from Yersinia pestis

3q62, resolution 1.40Å

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