7ezt: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
The | ==The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila== | ||
<StructureSection load='7ezt' size='340' side='right'caption='[[7ezt]], [[Resolution|resolution]] 2.81Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7ezt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Akkermansia_muciniphila_ATCC_BAA-835 Akkermansia muciniphila ATCC BAA-835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EZT FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ezt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ezt OCA], [https://pdbe.org/7ezt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ezt RCSB], [https://www.ebi.ac.uk/pdbsum/7ezt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ezt ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/H2136_AKKM8 H2136_AKKM8] Potentially capable of cleaving the specific glycoside linkages in the process of mucin degradation in human intestinal tract (Probable). Hydrolyzes synthetic substrate pNP-beta-GlcNAc with high activity and pNP-beta-GalNAc to a lot lesser extent. Does not hydrolyze pNP-alpha-GalNAc.<ref>PMID:31345574</ref> | |||
==See Also== | |||
*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Akkermansia muciniphila ATCC BAA-835]] | |||
[[Category: Large Structures]] | |||
[[Category: Bao R]] | |||
[[Category: Huang Q]] | |||
[[Category: Li CC]] | |||
[[Category: Liu TG]] | |||
[[Category: Luo GH]] | |||
[[Category: Mou XY]] | |||
[[Category: Song YJ]] | |||
[[Category: Tang XY]] | |||
[[Category: Zhao NL]] | |||
[[Category: Zhu YB]] | |||