3rt4: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rt4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3mu9 3mu9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RT4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rt4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3mu9 3mu9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RT4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LP5:(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL)+3-HYDROXYTETRADECANOATE'>LP5</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LP5:(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL)+3-HYDROXYTETRADECANOATE'>LP5</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rt4 OCA], [https://pdbe.org/3rt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rt4 RCSB], [https://www.ebi.ac.uk/pdbsum/3rt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rt4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rt4 OCA], [https://pdbe.org/3rt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rt4 RCSB], [https://www.ebi.ac.uk/pdbsum/3rt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rt4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).  
[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dey, S]]
[[Category: Dey S]]
[[Category: Dube, D]]
[[Category: Dube D]]
[[Category: Kaur, P]]
[[Category: Kaur P]]
[[Category: Mishra, B]]
[[Category: Mishra B]]
[[Category: Mitra, D K]]
[[Category: Mitra DK]]
[[Category: Sharma, P]]
[[Category: Sharma P]]
[[Category: Sharma, S]]
[[Category: Sharma S]]
[[Category: Singh, A]]
[[Category: Singh A]]
[[Category: Singh, N]]
[[Category: Singh N]]
[[Category: Singh, T P]]
[[Category: Singh TP]]
[[Category: Sinha, M]]
[[Category: Sinha M]]
[[Category: Antimicrobial]]
[[Category: Immune response]]
[[Category: Immune system]]
[[Category: Peptidoglycan binding]]
[[Category: Pgrp]]
[[Category: Secreted]]
Retrieved from "https://proteopedia.org/3rt4"