8d5v: Difference between revisions
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==WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera== | |||
<StructureSection load='8d5v' size='340' side='right'caption='[[8d5v]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8d5v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] and [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D5V FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d5v OCA], [https://pdbe.org/8d5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d5v RCSB], [https://www.ebi.ac.uk/pdbsum/8d5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d5v ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/WHIB6_MYCTU WHIB6_MYCTU] Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity). The apo-form has been shown to act as a protein disulfide reductase.<ref>PMID:19016840</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Wan T]] | |||
[[Category: Zhang LM]] | |||
Revision as of 08:17, 14 June 2023
WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera
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