3ssb: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='3ssb' size='340' side='right'caption='[[3ssb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3ssb' size='340' side='right'caption='[[3ssb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ssb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] and [https://en.wikipedia.org/wiki/Galme Galme]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ssb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] and [https://en.wikipedia.org/wiki/Galleria_mellonella Galleria mellonella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IMPI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7137 GALME])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssb OCA], [https://pdbe.org/3ssb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssb RCSB], [https://www.ebi.ac.uk/pdbsum/3ssb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssb OCA], [https://pdbe.org/3ssb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssb RCSB], [https://www.ebi.ac.uk/pdbsum/3ssb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease. [[https://www.uniprot.org/uniprot/IMPI_GALME IMPI_GALME]] Inhibits thermolysin, bacillolysin and pseudolysin, B.polymyxa metalloprotease and human MMP1 and MMP3. No activity on trypsin or cysteine protease papain.<ref>PMID:15115439</ref> <ref>PMID:9738891</ref> 
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.


==See Also==
==See Also==
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Galme]]
[[Category: Galleria mellonella]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thermolysin]]
[[Category: Arolas JL]]
[[Category: Arolas, J L]]
[[Category: Botelho TO]]
[[Category: Botelho, T O]]
[[Category: Gomis-Ruth FX]]
[[Category: Gomis-Ruth, F X]]
[[Category: Vilcinskas A]]
[[Category: Vilcinskas, A]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Metalloprotease thermolysin inhibitor]]
[[Category: Secreted]]
[[Category: Thermolysin fold - family i8 fold]]
[[Category: Zn binding]]
Retrieved from "https://proteopedia.org/3ssb"