3t7f: Difference between revisions

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<StructureSection load='3t7f' size='340' side='right'caption='[[3t7f]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
<StructureSection load='3t7f' size='340' side='right'caption='[[3t7f]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t7f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7F FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t7f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7F FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3t7e|3t7e]], [[3t7g|3t7g]], [[3t7h|3t7h]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG7, APG7, CVT2, YHR171W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7f OCA], [https://pdbe.org/3t7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7f RCSB], [https://www.ebi.ac.uk/pdbsum/3t7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7f OCA], [https://pdbe.org/3t7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7f RCSB], [https://www.ebi.ac.uk/pdbsum/3t7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST]] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>
[https://www.uniprot.org/uniprot/ATG7_YEAST ATG7_YEAST] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.<ref>PMID:9759731</ref> <ref>PMID:8224160</ref> <ref>PMID:7593182</ref> <ref>PMID:10233148</ref> <ref>PMID:10233150</ref> <ref>PMID:11100732</ref> <ref>PMID:11149920</ref> <ref>PMID:12965207</ref> <ref>PMID:15277523</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Deng, A]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Green, D R]]
[[Category: Deng A]]
[[Category: Hammel, M]]
[[Category: Green DR]]
[[Category: Kaiser, S E]]
[[Category: Hammel M]]
[[Category: Kurinov, I]]
[[Category: Kaiser SE]]
[[Category: Nourse, A]]
[[Category: Kurinov I]]
[[Category: Rock, C O]]
[[Category: Nourse A]]
[[Category: Schulman, B A]]
[[Category: Rock CO]]
[[Category: Taherbhoy, A M]]
[[Category: Schulman BA]]
[[Category: Tait, S W]]
[[Category: Taherbhoy AM]]
[[Category: Williams, A H]]
[[Category: Tait SW]]
[[Category: Atg7]]
[[Category: Williams AH]]
[[Category: Autophagy]]
[[Category: E1]]
[[Category: Ligase]]
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