7t3k: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7t3k is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of Csy-AcrIF24 dimer==

~~Authors~~: ~~Mukherjee~~, I.A., ~~Chang~~, L.

== Structural highlights ==

<table><tr><td colspan='2'>[[7t3k]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas Pseudomonas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T3K FirstGlance]. <br>

~~Description~~: ~~Cryo-EM structure~~ of Csy~~-AcrIF24 dimer~~

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t3k OCA], [https://pdbe.org/7t3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t3k RCSB], [https://www.ebi.ac.uk/pdbsum/7t3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t3k ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

[[Category: ~~Mukherjee, I.A~~]]

== Function ==

[[Category: Chang, L]]

[[https://www.uniprot.org/uniprot/CSY1_PSEAB CSY1_PSEAB]] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 and Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). Involved in crRNA production or stability. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.<ref>PMID:21398535</ref> <ref>PMID:22522703</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Pseudomonas]]

[[Category: Chang L]]

[[Category: Mukherjee IA]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7t3k is ON HOLD  until Paper Publication
+==Cryo-EM structure of Csy-AcrIF24 dimer==
+<StructureSection load='7t3k' size='340' side='right'caption='[[7t3k]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-Authors: Mukherjee, I.A., Chang, L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7t3k]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas Pseudomonas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T3K FirstGlance]. <br>
-Description: Cryo-EM structure of Csy-AcrIF24 dimer
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t3k OCA], [https://pdbe.org/7t3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t3k RCSB], [https://www.ebi.ac.uk/pdbsum/7t3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t3k ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Mukherjee, I.A]]
+== Function ==
-[[Category: Chang, L]]
+[[https://www.uniprot.org/uniprot/CSY1_PSEAB CSY1_PSEAB]] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 and Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). Involved in crRNA production or stability. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.<ref>PMID:21398535</ref> <ref>PMID:22522703</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Pseudomonas]]
+[[Category: Chang L]]
+[[Category: Mukherjee IA]]