3txs: Difference between revisions

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<StructureSection load='3txs' size='340' side='right'caption='[[3txs]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
<StructureSection load='3txs' size='340' side='right'caption='[[3txs]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3txs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeromonas_phage_40rr2.8t Aeromonas phage 40rr2.8t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TXS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3txs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeromonas_virus_44RR2 Aeromonas virus 44RR2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TXS FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3txq|3txq]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">16, gene 16 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=115987 Aeromonas phage 40RR2.8t])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3txs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3txs OCA], [https://pdbe.org/3txs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3txs RCSB], [https://www.ebi.ac.uk/pdbsum/3txs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3txs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3txs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3txs OCA], [https://pdbe.org/3txs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3txs RCSB], [https://www.ebi.ac.uk/pdbsum/3txs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3txs ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/Q6U9F0_9CAUD Q6U9F0_9CAUD]
Tailed DNA bacteriophages assemble empty procapsids that are subsequently filled with the viral genome by means of a DNA packaging machine situated at a special fivefold vertex. The packaging machine consists of a "small terminase" and a "large terminase" component. One of the functions of the small terminase is to initiate packaging of the viral genome, whereas the large terminase is responsible for the ATP-powered translocation of DNA. The small terminase subunit has three domains, an N-terminal DNA-binding domain, a central oligomerization domain, and a C-terminal domain for interacting with the large terminase. Here we report structures of the central domain in two different oligomerization states for a small terminase from the T4 family of phages. In addition, we report biochemical studies that establish the function for each of the small terminase domains. On the basis of the structural and biochemical information, we propose a model for DNA packaging initiation.
 
Structure and function of the small terminase component of the DNA packaging machine in T4-like bacteriophages.,Sun S, Gao S, Kondabagil K, Xiang Y, Rossmann MG, Rao VB Proc Natl Acad Sci U S A. 2011 Dec 29. PMID:22207623<ref>PMID:22207623</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3txs" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aeromonas phage 40rr2 8t]]
[[Category: Aeromonas virus 44RR2]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rossmann, M G]]
[[Category: Rossmann MG]]
[[Category: Sun, S]]
[[Category: Sun S]]
[[Category: Xiang, Y]]
[[Category: Xiang Y]]
[[Category: Helix]]
[[Category: Small terminase]]
[[Category: Viral protein]]

Latest revision as of 13:42, 14 March 2024

Crystal Structure of phage 44RR small terminase gp16

3txs, resolution 1.81Å

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