3u83: Difference between revisions
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<StructureSection load='3u83' size='340' side='right'caption='[[3u83]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='3u83' size='340' side='right'caption='[[3u83]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3u83]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3u83]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U83 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.499Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG6:1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE'>PG6</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u83 OCA], [https://pdbe.org/3u83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u83 RCSB], [https://www.ebi.ac.uk/pdbsum/3u83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u83 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u83 OCA], [https://pdbe.org/3u83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u83 RCSB], [https://www.ebi.ac.uk/pdbsum/3u83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u83 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/NECT1_HUMAN NECT1_HUMAN] Isolated cleft lip;Cleft lip/palate-ectodermal dysplasia syndrome;Cleft lip and alveolus;Cleft lip/palate. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NECT1_HUMAN NECT1_HUMAN] Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4. Has some neurite outgrowth-promoting activity.<ref>PMID:21980294</ref> (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1, herpes simplex virus 2/HHV-2, and pseudorabies virus/PRV.<ref>PMID:7721102</ref> <ref>PMID:9657005</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Fan | [[Category: Fan Z]] | ||
[[Category: Gao | [[Category: Gao GF]] | ||
[[Category: Guo | [[Category: Guo Z]] | ||
[[Category: Lu | [[Category: Lu G]] | ||
[[Category: Qi | [[Category: Qi J]] | ||
[[Category: Shi | [[Category: Shi Y]] | ||
[[Category: Wang | [[Category: Wang J]] | ||
[[Category: Yan | [[Category: Yan J]] | ||
[[Category: Zhang | [[Category: Zhang N]] | ||
