Phytase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Function == | == Function == | ||
'''Phytase''' (PHYT) catalyzes the hydrolysis of phytate (myo-inositol hexakisphosphate) to myo-inositol and inorganic phosphate <ref>PMID:9025298</ref>. PHYT are a subclass of the histidine acid phosphatase<ref>PMID:9025298</ref>. Phytate is the main phosphorus storage system in plant seeds. | '''Phytase''' (PHYT) catalyzes the hydrolysis of phytate (myo-inositol hexakisphosphate) to myo-inositol and inorganic phosphate <ref>PMID:9025298</ref>. PHYT are a subclass of the histidine acid phosphatase<ref>PMID:9025298</ref>. Phytate is the main phosphorus storage system in plant seeds. Phytate is indigestible by monogastric animals and humans<ref>PMID:32271147</ref>. | ||
== Relevance == | == Relevance == | ||
PHYT is found in plant material and is used to increase the nutritional quality of grains, legumes, seeds and corn. | PHYT is found in plant material and is used to increase the nutritional quality of grains, legumes, seeds and corn. PHYT is used as a dietary supplement in broiler nutrition<ref>PMID:31610823</ref>. Studies show that supplementing PHYT can reduce the need for calcium phosphate and increase digestive health. | ||
== Structural highlights == | == Structural highlights == | ||
The 3D structure of the complex between phytase and myo-inositol hexakisphosphate shows the extensive contacts of the phosphoryl groups of the substrate binding in the highly basic binding pocket<ref>PMID:22139834</ref>. | The 3D structure of the complex between phytase and myo-inositol hexakisphosphate shows the extensive contacts of the phosphoryl groups of the substrate binding in the highly basic binding pocket<ref>PMID:22139834</ref>. <scene name='91/917455/Cv/2'>TextToBeDisplayed</scene> | ||
==3D structures of phytase== | ==3D structures of phytase== | ||
