8dkd: Difference between revisions

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'''Unreleased structure'''


The entry 8dkd is ON HOLD  until 2024-01-05
==Sliding clamp from M. thermoresistibile==
 
<StructureSection load='8dkd' size='340' side='right'caption='[[8dkd]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
Authors: Kapur, M.K., Gray, O.J., Honzatko, R.H., Nelson, S.N.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8dkd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_thermoresistibile_ATCC_19527 Mycolicibacterium thermoresistibile ATCC 19527]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DKD FirstGlance]. <br>
Description: Sliding clamp from M. thermoresistibile
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dkd OCA], [https://pdbe.org/8dkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dkd RCSB], [https://www.ebi.ac.uk/pdbsum/8dkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dkd ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Honzatko, R.H]]
== Function ==
[[Category: Nelson, S.N]]
[https://www.uniprot.org/uniprot/G7CIP4_MYCT3 G7CIP4_MYCT3] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804]
[[Category: Gray, O.J]]
__TOC__
[[Category: Kapur, M.K]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycolicibacterium thermoresistibile ATCC 19527]]
[[Category: Gray OJ]]
[[Category: Honzatko RH]]
[[Category: Kapur MK]]
[[Category: Nelson SN]]
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