7p42: Difference between revisions
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==Crystal structure of IpgC in complex with a follow-up compound based on J2== | ==Crystal structure of IpgC in complex with a follow-up compound based on J2== | ||
<StructureSection load='7p42' size='340' side='right'caption='[[7p42]]' scene=''> | <StructureSection load='7p42' size='340' side='right'caption='[[7p42]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P42 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7p42]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P42 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p42 OCA], [https://pdbe.org/7p42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p42 RCSB], [https://www.ebi.ac.uk/pdbsum/7p42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p42 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5I8:2-(4,6-dimethylpyrimidin-2-yl)-3H-isoindol-1-imine'>5I8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p42 OCA], [https://pdbe.org/7p42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p42 RCSB], [https://www.ebi.ac.uk/pdbsum/7p42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p42 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Shigella flexneri]] | |||
[[Category: Gardonyi M]] | [[Category: Gardonyi M]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
[[Category: Klebe G]] | [[Category: Klebe G]] | ||
Revision as of 04:55, 8 September 2022
Crystal structure of IpgC in complex with a follow-up compound based on J2
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