FirstGlance/How To Measure A Virus Capsid: Difference between revisions
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(EEEV) consists of three distinct protein sequences, and a total of 720 chains. It has nearly 2 million non-hydrogen atoms (so about 3.6 million atoms including hydrogen). The structure [[6mx4]] determined by electron microscopy (4.4 Å resolution) has 12 chains, with instructions for constructing the entire capsid. | (EEEV) consists of three distinct protein sequences, and a total of 720 chains. It has nearly 2 million non-hydrogen atoms (so about 3.6 million atoms including hydrogen). The structure [[6mx4]] determined by electron microscopy (4.4 Å resolution) has 12 chains, with instructions for constructing the entire capsid using 60 copies of the asymmetric unit. | ||
[[FirstGlance in Jmol]] automatically constructs the capsid, and simplifies it to a subset of alpha carbon atoms small enough (not more than 25,000) to be analyzed efficiently in the FirstGlance and JSmol, both of which run in the Javascript of the web browser. FirstGlance offers a number of useful color schemes, including distance from center, colors that distinguish sequence-identical groups of chains, and amino-to-carboxy rainbow. When the structure is small enough that all alpha carbons can be displayed (not more than 250,000 alpha carbons; EEEV has 242,340), it can also be colored by charge, hydrophobic vs. polar, or evolutionary conservation. | [[FirstGlance in Jmol]] automatically constructs the capsid, and simplifies it to a subset of alpha carbon atoms small enough (not more than 25,000) to be analyzed efficiently in the FirstGlance and JSmol, both of which run in the Javascript of the web browser. FirstGlance offers a number of useful color schemes, including distance from center, colors that distinguish sequence-identical groups of chains, and amino-to-carboxy rainbow. When the structure is small enough that all alpha carbons can be displayed (not more than 250,000 alpha carbons; EEEV has 242,340), it can also be colored by charge, hydrophobic vs. polar, or evolutionary conservation. | ||
</StructureSection> | </StructureSection> | ||
