7uwn: Difference between revisions
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==== | ==Structure of the IL-17A-IL-17RA-IL-17RC ternary complex== | ||
<StructureSection load='7uwn' size='340' side='right'caption='[[7uwn]]' scene=''> | <StructureSection load='7uwn' size='340' side='right'caption='[[7uwn]], [[Resolution|resolution]] 3.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7uwn]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UWN FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwn OCA], [https://pdbe.org/7uwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwn RCSB], [https://www.ebi.ac.uk/pdbsum/7uwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwn ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uwn OCA], [https://pdbe.org/7uwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uwn RCSB], [https://www.ebi.ac.uk/pdbsum/7uwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uwn ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN]] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Caveney NA]] | ||
[[Category: Garcia KC]] | |||
[[Category: Jude KM]] | |||
[[Category: Wilson SC]] | |||
Revision as of 16:49, 7 September 2022
Structure of the IL-17A-IL-17RA-IL-17RC ternary complex
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