7y7z: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~7y7z is ON HOLD until Paper Publication~~

==Cryo-EM structure of human GABA transporter GAT1 bound with tiagabine in NaCl solution in an inward-open state at 3.2 angstrom==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7y7z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y7Z FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TGI:Tiagabine'>TGI</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y7z OCA], [https://pdbe.org/7y7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y7z RCSB], [https://www.ebi.ac.uk/pdbsum/7y7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y7z ProSAT]</span></td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN] Myoclonic-astatic epilepsy. The disease is caused by variants affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN] Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Huang J]]

[[Category: Kong F]]

[[Category: Lei J]]

[[Category: Tan J]]

[[Category: Yan C]]

[[Category: Yuan Y]]

[[Category: Zhu A]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7y7z is ON HOLD  until Paper Publication
+==Cryo-EM structure of human GABA transporter GAT1 bound with tiagabine in NaCl solution in an inward-open state at 3.2 angstrom==
+<StructureSection load='7y7z' size='340' side='right'caption='[[7y7z]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7y7z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y7Z FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TGI:Tiagabine'>TGI</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y7z OCA], [https://pdbe.org/7y7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y7z RCSB], [https://www.ebi.ac.uk/pdbsum/7y7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y7z ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN] Myoclonic-astatic epilepsy. The disease is caused by variants affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/SC6A1_HUMAN SC6A1_HUMAN] Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Huang J]]
+[[Category: Kong F]]
+[[Category: Lei J]]
+[[Category: Tan J]]
+[[Category: Yan C]]
+[[Category: Yuan Y]]
+[[Category: Zhu A]]