8a8f: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry 8a8f~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8a8f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A8F OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8A8F FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8a8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a8f OCA], [https://pdbe.org/8a8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a8f RCSB], [https://www.ebi.ac.uk/pdbsum/8a8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a8f ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/PP12_YEAST PP12_YEAST] Involved in control of glycogen metabolism, meiosis, translation, chromosome segregation, cell polarity and G2/M cell cycle progression. PP1 may act in opposition to the IPL1 protein kinase in regulating chromosome segregation by dephosphorylating H3S10ph. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may function as a specific activator of the dynein complex. Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Saccharomyces cerevisiae]]

[[Category: Bellini D]]

[[Category: Carminati M]]

[[Category: Manav CM]]

[[Category: Passmore LA]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8a8f is ON HOLD  until Paper Publication
+==Crystal structure of Glc7 phosphatase in complex with the regulatory region of Ref2==
+<StructureSection load='8a8f' size='340' side='right'caption='[[8a8f]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8a8f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A8F FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a8f OCA], [https://pdbe.org/8a8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a8f RCSB], [https://www.ebi.ac.uk/pdbsum/8a8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a8f ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PP12_YEAST PP12_YEAST] Involved in control of glycogen metabolism, meiosis, translation, chromosome segregation, cell polarity and G2/M cell cycle progression. PP1 may act in opposition to the IPL1 protein kinase in regulating chromosome segregation by dephosphorylating H3S10ph. The BUD14-GLC7 complex is necessary to regulate microtubule dynamics at the cortex and may function as a specific activator of the dynein complex.  Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Component of the APT complex, which may be involved in polyadenylation-independent transcript 3'-end formation.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae]]
+[[Category: Bellini D]]
+[[Category: Carminati M]]
+[[Category: Manav CM]]
+[[Category: Passmore LA]]