1htm: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1htm.gif|left|200px]]
[[Image:1htm.png|left|200px]]


<!--
<!--
Line 12: Line 12:




==Overview==
{{ABSTRACT_8072525}}
Low pH induces a conformational change in the influenza virus haemagglutinin, which then mediates fusion of the viral and host cell membranes. The three-dimensional structure of a fragment of the haemagglutinin in this conformation reveals a major refolding of the secondary and tertiary structure of the molecule. The apolar fusion peptide moves at least 100 A to one tip of the molecule. At the other end a helical segment unfolds, a subdomain relocates reversing the chain direction, and part of the structure becomes disordered.


==About this Structure==
==About this Structure==
1HTM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. The following page contains interesting information on the relation of 1HTM with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb76_1.html Hemagglutinin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTM OCA].  
1HTM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. The following page contains interesting information on the relation of 1HTM with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb76_1.html Hemagglutinin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTM OCA].  
==Reference==
Structure of influenza haemagglutinin at the pH of membrane fusion., Bullough PA, Hughson FM, Skehel JJ, Wiley DC, Nature. 1994 Sep 1;371(6492):37-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8072525 8072525]
[[Category: Bacteria]]
[[Category: Bacteria]]
[[Category: Hemagglutinin]]
[[Category: Hemagglutinin]]
Line 28: Line 24:
[[Category: Wiley, D C.]]
[[Category: Wiley, D C.]]
[[Category: Influenza virus hemagglutinin]]
[[Category: Influenza virus hemagglutinin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 19:12:58 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:30:29 2008''