7p8l: Difference between revisions
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==== | ==Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG== | ||
<StructureSection load='7p8l' size='340' side='right'caption='[[7p8l]]' scene=''> | <StructureSection load='7p8l' size='340' side='right'caption='[[7p8l]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7p8l]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P8L FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p8l OCA], [https://pdbe.org/7p8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p8l RCSB], [https://www.ebi.ac.uk/pdbsum/7p8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p8l ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8OG:8-OXO-2-DEOXY-GUANOSINE-5-MONOPHOSPHATE'>8OG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p8l OCA], [https://pdbe.org/7p8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p8l RCSB], [https://www.ebi.ac.uk/pdbsum/7p8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p8l ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/AGOG_PYRAB AGOG_PYRAB]] DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pyrococcus abyssi GE5]] | ||
[[Category: Synthetic construct]] | |||
[[Category: Castaing B]] | |||
[[Category: Coste F]] | |||
[[Category: Flament D]] | |||
Revision as of 03:08, 8 September 2022
Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG
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