3wa1: Difference between revisions
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<StructureSection load='3wa1' size='340' side='right'caption='[[3wa1]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='3wa1' size='340' side='right'caption='[[3wa1]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3wa1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3wa1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WA1 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wa1 OCA], [https://pdbe.org/3wa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wa1 RCSB], [https://www.ebi.ac.uk/pdbsum/3wa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wa1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wa1 OCA], [https://pdbe.org/3wa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wa1 RCSB], [https://www.ebi.ac.uk/pdbsum/3wa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wa1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/BINB2_LYSSH BINB2_LYSSH] Component of a binary toxin active against Culex and some Aedes mosquito larvae (PubMed:1512580, PubMed:8419297). This subunit is responsible for localized binding to specific regions of the host larval gut. The individual subunits are not toxic. BinAB and this subunit alone bind to the gastric caecum and posterior midgut of C.quinquefasciatus larvae. Binary toxin internalization into host gut cells requires both proteins. Does not bind to the midgut of Aedes aegypti (PubMed:1512580). Toxic to Aedes atropalpus mosquito larvae; mortality towards both C.quinquefasciatus and A.atropalpus is maximal by 48 hours. A.aegypti is not very susceptible to this toxin (PubMed:8419297). Binding component of binary toxin. The 51 kDa polypeptide acts synergetically with the 42 kDa polypeptide for expression of a larvicidal toxin.<ref>PMID:1512580</ref> <ref>PMID:8419297</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Boonserm | [[Category: Lysinibacillus sphaericus]] | ||
[[Category: Chimnaronk | [[Category: Boonserm P]] | ||
[[Category: Promdonkoy | [[Category: Chimnaronk S]] | ||
[[Category: Srisucharitpanit | [[Category: Promdonkoy B]] | ||
[[Category: Tanaka | [[Category: Srisucharitpanit K]] | ||
[[Category: Yao | [[Category: Tanaka I]] | ||
[[Category: Yao M]] | |||
