7lr9: Difference between revisions
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==Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem== | ==Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem== | ||
<StructureSection load='7lr9' size='340' side='right'caption='[[7lr9]]' scene=''> | <StructureSection load='7lr9' size='340' side='right'caption='[[7lr9]], [[Resolution|resolution]] 1.47Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LR9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7lr9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LR9 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lr9 OCA], [https://pdbe.org/7lr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lr9 RCSB], [https://www.ebi.ac.uk/pdbsum/7lr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lr9 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8YF:(2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole+-5-carboxylic+acid'>8YF</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lr9 OCA], [https://pdbe.org/7lr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lr9 RCSB], [https://www.ebi.ac.uk/pdbsum/7lr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lr9 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. | |||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Klebsiella pneumoniae]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Furey I]] | [[Category: Furey I]] | ||
