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<StructureSection load='3wx9' size='340' side='right'caption='[[3wx9]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
<StructureSection load='3wx9' size='340' side='right'caption='[[3wx9]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wx9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WX9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wx9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WX9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EE:4-(2-AMINOPHENYL)-2,4-DIOXOBUTANOIC+ACID'>3EE</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=G9A:(2E)-PENT-2-ENEDIOIC+ACID'>G9A</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=KYA:4-HYDROXYQUINOLINE-2-CARBOXYLIC+ACID'>KYA</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3av7|3av7]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3EE:4-(2-AMINOPHENYL)-2,4-DIOXOBUTANOIC+ACID'>3EE</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=G9A:(2E)-PENT-2-ENEDIOIC+ACID'>G9A</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=KYA:4-HYDROXYQUINOLINE-2-CARBOXYLIC+ACID'>KYA</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAT, PH0207 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wx9 OCA], [https://pdbe.org/3wx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wx9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wx9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wx9 OCA], [https://pdbe.org/3wx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wx9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wx9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O57946_PYRHO O57946_PYRHO]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Angkawidjaja, C]]
[[Category: Angkawidjaja C]]
[[Category: Kanaya, S]]
[[Category: Kanaya S]]
[[Category: Koga, Y]]
[[Category: Koga Y]]
[[Category: Okada, K]]
[[Category: Okada K]]
[[Category: Aminotransferase]]
[[Category: Kyn binding]]
[[Category: Transferase]]

Latest revision as of 13:32, 8 November 2023

Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA

3wx9, resolution 1.58Å

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