7ugw: Difference between revisions

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====

==M. tuberculosis DNA gyrase cleavage core bound to DNA and evybactin==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance].

<table><tr><td colspan='2'>[[7ugw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv], [https://en.wikipedia.org/wiki/Photorhabdus_noenieputensis Photorhabdus noenieputensis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UGW OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7UGW FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7ugw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ugw OCA], [https://pdbe.org/7ugw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ugw RCSB], [https://www.ebi.ac.uk/pdbsum/7ugw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ugw ProSAT]</td></tr>

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAR:D-ARGININE'>DAR</scene>, <scene name='pdbligand=DSN:D-SERINE'>DSN</scene>, <scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MHS:N1-METHYLATED+HISTIDINE'>MHS</scene>, <scene name='pdbligand=NLF:N-formyl-L-tryptophan'>NLF</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7ugw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ugw OCA], [https://pdbe.org/7ugw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ugw RCSB], [https://www.ebi.ac.uk/pdbsum/7ugw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ugw ProSAT]</td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/GYRA_MYCTU GYRA_MYCTU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: ~~Z-disk~~]]

[[Category: Mycobacterium tuberculosis H37Rv]]

[[Category: Photorhabdus noenieputensis]]

[[Category: Synthetic construct]]

[[Category: Berger JM]]

[[Category: Hauk G]]

[[Category: Imai Y]]

[[Category: Lewis K]]

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-====
+==M. tuberculosis DNA gyrase cleavage core bound to DNA and evybactin==
-<StructureSection load='7ugw' size='340' side='right'caption='[[7ugw]]' scene=''>
+<StructureSection load='7ugw' size='340' side='right'caption='[[7ugw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7ugw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv], [https://en.wikipedia.org/wiki/Photorhabdus_noenieputensis Photorhabdus noenieputensis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UGW FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ugw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ugw OCA], [https://pdbe.org/7ugw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ugw RCSB], [https://www.ebi.ac.uk/pdbsum/7ugw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ugw ProSAT]</span></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAR:D-ARGININE'>DAR</scene>, <scene name='pdbligand=DSN:D-SERINE'>DSN</scene>, <scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MHS:N1-METHYLATED+HISTIDINE'>MHS</scene>, <scene name='pdbligand=NLF:N-formyl-L-tryptophan'>NLF</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ugw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ugw OCA], [https://pdbe.org/7ugw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ugw RCSB], [https://www.ebi.ac.uk/pdbsum/7ugw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ugw ProSAT]</span></td></tr>
 </table>
+== Function ==
+[[https://www.uniprot.org/uniprot/GYRA_MYCTU GYRA_MYCTU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
+[[Category: Photorhabdus noenieputensis]]
+[[Category: Synthetic construct]]
+[[Category: Berger JM]]
+[[Category: Hauk G]]
+[[Category: Imai Y]]
+[[Category: Lewis K]]