3zm7: Difference between revisions

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<StructureSection load='3zm7' size='340' side='right'caption='[[3zm7]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='3zm7' size='340' side='right'caption='[[3zm7]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zm7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZM7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zm7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZM7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zm7 OCA], [https://pdbe.org/3zm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zm7 RCSB], [https://www.ebi.ac.uk/pdbsum/3zm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zm7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zm7 OCA], [https://pdbe.org/3zm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zm7 RCSB], [https://www.ebi.ac.uk/pdbsum/3zm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zm7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/I6WX66_MYCTU I6WX66_MYCTU]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).[HAMAP-Rule:MF_01898]
[https://www.uniprot.org/uniprot/GYRB_MYCTU GYRB_MYCTU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Agrawal, A]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Aubry, A]]
[[Category: Agrawal A]]
[[Category: Bax, B]]
[[Category: Aubry A]]
[[Category: Hann, M]]
[[Category: Bax B]]
[[Category: Mayer, C]]
[[Category: Hann M]]
[[Category: Mossakowska, D]]
[[Category: Mayer C]]
[[Category: Petrella, S]]
[[Category: Mossakowska D]]
[[Category: Roue, M]]
[[Category: Petrella S]]
[[Category: Spitzfaden, C]]
[[Category: Roue M]]
[[Category: Volker, C]]
[[Category: Spitzfaden C]]
[[Category: Ghkl domain]]
[[Category: Volker C]]
[[Category: Isomerase]]
[[Category: Type iia topoisomerase]]
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