4a7a: Difference between revisions

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<StructureSection load='4a7a' size='340' side='right'caption='[[4a7a]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4a7a' size='340' side='right'caption='[[4a7a]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A7A FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A7A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=RGZ:(R)-ROSIGLITAZONE'>RGZ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2c67|2c67]], [[3zyx|3zyx]], [[1s3e|1s3e]], [[2c73|2c73]], [[2v60|2v60]], [[1oj9|1oj9]], [[1ojd|1ojd]], [[2vz2|2vz2]], [[1s3b|1s3b]], [[2c66|2c66]], [[2xfo|2xfo]], [[2bk5|2bk5]], [[2c70|2c70]], [[1h8r|1h8r]], [[2xfn|2xfn]], [[2bk3|2bk3]], [[2c76|2c76]], [[2vrl|2vrl]], [[1oja|1oja]], [[2v5z|2v5z]], [[2xfu|2xfu]], [[2byb|2byb]], [[2vrm|2vrm]], [[2c65|2c65]], [[2xcg|2xcg]], [[2c64|2c64]], [[2xfp|2xfp]], [[2bk4|2bk4]], [[2c75|2c75]], [[2v61|2v61]], [[2c72|2c72]], [[1s2y|1s2y]], [[4a79|4a79]], [[1gos|1gos]], [[1s2q|1s2q]], [[2xfq|2xfq]], [[1ojc|1ojc]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=RGZ:(R)-ROSIGLITAZONE'>RGZ</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Monoamine_oxidase Monoamine oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a7a OCA], [https://pdbe.org/4a7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a7a RCSB], [https://www.ebi.ac.uk/pdbsum/4a7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a7a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a7a OCA], [https://pdbe.org/4a7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a7a RCSB], [https://www.ebi.ac.uk/pdbsum/4a7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a7a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN]] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.  
[https://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Monoamine oxidase]]
[[Category: Aldeco M]]
[[Category: Aldeco, M]]
[[Category: Binda C]]
[[Category: Binda, C]]
[[Category: Edmondson DE]]
[[Category: Edmondson, D E]]
[[Category: Geldenhuys WJ]]
[[Category: Geldenhuys, W J]]
[[Category: Mattevi A]]
[[Category: Mattevi, A]]
[[Category: Tortorici M]]
[[Category: Tortorici, M]]
[[Category: Anti-diabetes drug]]
[[Category: Neurodegeneration]]
[[Category: Oxidoreductase]]
[[Category: Parkinson's disease]]
Retrieved from "https://proteopedia.org/4a7a"