8dwt: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8dwt is ~~ON HOLD until Paper Publication~~

==SPOP W22R Form 2==

~~Authors~~: ~~Cuneo~~, M.J., ~~Mittag~~, T., ~~O''Flynn~~, B., Lo, Y.H.

== Structural highlights ==

<table><tr><td colspan='2'>[[8dwt]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DWT FirstGlance]. <br>

~~Description~~: ~~SPOP W22R Form 2~~

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dwt OCA], [https://pdbe.org/8dwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dwt RCSB], [https://www.ebi.ac.uk/pdbsum/8dwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dwt ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

[[Category: Cuneo~~, M.J~~]]

== Function ==

[[Category: Lo~~, Y.H~~]]

[https://www.uniprot.org/uniprot/SPOP_HUMAN SPOP_HUMAN] Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.<ref>PMID:14528312</ref> <ref>PMID:15897469</ref> <ref>PMID:16524876</ref>

[[Category: Mittag, T]]

== References ==

[[Category: O''Flynn, B]]

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Cuneo MJ]]

[[Category: Lo YH]]

[[Category: Mittag T]]

[[Category: O'Flynn B]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8dwt is ON HOLD  until Paper Publication
+==SPOP W22R Form 2==
+<StructureSection load='8dwt' size='340' side='right'caption='[[8dwt]], [[Resolution|resolution]] 6.20&Aring;' scene=''>
-Authors: Cuneo, M.J., Mittag, T., O''Flynn, B., Lo, Y.H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8dwt]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DWT FirstGlance]. <br>
-Description: SPOP W22R Form 2
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dwt OCA], [https://pdbe.org/8dwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dwt RCSB], [https://www.ebi.ac.uk/pdbsum/8dwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dwt ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Cuneo, M.J]]
+== Function ==
-[[Category: Lo, Y.H]]
+[https://www.uniprot.org/uniprot/SPOP_HUMAN SPOP_HUMAN] Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.<ref>PMID:14528312</ref> <ref>PMID:15897469</ref> <ref>PMID:16524876</ref>
-[[Category: Mittag, T]]
+== References ==
-[[Category: O''Flynn, B]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Cuneo MJ]]
+[[Category: Lo YH]]
+[[Category: Mittag T]]
+[[Category: O'Flynn B]]