8cub: Difference between revisions
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==== | ==Crystal Structure of ABCG5/G8 in Complex with Cholesterol== | ||
<StructureSection load='8cub' size='340' side='right'caption='[[8cub]]' scene=''> | <StructureSection load='8cub' size='340' side='right'caption='[[8cub]], [[Resolution|resolution]] 4.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[8cub]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CUB FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cub OCA], [https://pdbe.org/8cub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cub RCSB], [https://www.ebi.ac.uk/pdbsum/8cub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cub ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cub OCA], [https://pdbe.org/8cub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cub RCSB], [https://www.ebi.ac.uk/pdbsum/8cub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cub ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | |||
[[https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN]] Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN]] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Farhat D]] | ||
[[Category: Lee JY]] | |||
[[Category: Rezaei F]] | |||
