4bit: Difference between revisions
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==solution structure of cerebral dopamine neurotrophic factor (CDNF)== | ==solution structure of cerebral dopamine neurotrophic factor (CDNF)== | ||
<StructureSection load='4bit' size='340' side='right'caption='[[4bit | <StructureSection load='4bit' size='340' side='right'caption='[[4bit]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bit]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4bit]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BIT FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bit OCA], [https://pdbe.org/4bit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bit RCSB], [https://www.ebi.ac.uk/pdbsum/4bit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bit ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bit OCA], [https://pdbe.org/4bit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bit RCSB], [https://www.ebi.ac.uk/pdbsum/4bit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bit ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CDNF_HUMAN CDNF_HUMAN] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Almeida | [[Category: Almeida MS]] | ||
[[Category: Cabral | [[Category: Cabral KMS]] | ||
[[Category: Foguel | [[Category: Foguel D]] | ||
[[Category: Herrmann | [[Category: Herrmann T]] | ||
[[Category: Latge | [[Category: Latge C]] | ||
[[Category: Raymundo | [[Category: Raymundo DP]] | ||