8ea6: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8ea6 is ~~ON HOLD~~

==NKG2D complexed with inhibitor 3e==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8ea6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EA6 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VMB:N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(trifluoromethyl)[1,1-biphenyl]-2-carboxamide'>VMB</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ea6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ea6 OCA], [https://pdbe.org/8ea6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ea6 RCSB], [https://www.ebi.ac.uk/pdbsum/8ea6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ea6 ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Grant JC]]

[[Category: Karpowich NK]]

[[Category: Sharma S]]

[[Category: Thompson AA]]

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-'''Unreleased structure'''
-The entry 8ea6 is ON HOLD
+==NKG2D complexed with inhibitor 3e==
+<StructureSection load='8ea6' size='340' side='right'caption='[[8ea6]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8ea6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EA6 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VMB:N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(trifluoromethyl)[1,1-biphenyl]-2-carboxamide'>VMB</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ea6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ea6 OCA], [https://pdbe.org/8ea6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ea6 RCSB], [https://www.ebi.ac.uk/pdbsum/8ea6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ea6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Grant JC]]
+[[Category: Karpowich NK]]
+[[Category: Sharma S]]
+[[Category: Thompson AA]]