8a43: Difference between revisions

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</table>

== Disease ==

[[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN]] Treacher-Collins syndrome. The disease is caused by variants affecting the gene represented in this entry.

[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN] Treacher-Collins syndrome. The disease is caused by variants affecting the gene represented in this entry.

== Function ==

[[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.<ref>PMID:16809778</ref>

[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.<ref>PMID:16809778</ref>

== References ==

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@@ Line 7: / Line 7: @@
 </table>
 == Disease ==
-[[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN]] Treacher-Collins syndrome. The disease is caused by variants affecting the gene represented in this entry.
+[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN] Treacher-Collins syndrome. The disease is caused by variants affecting the gene represented in this entry.
 == Function ==
-[[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.<ref>PMID:16809778</ref>
+[https://www.uniprot.org/uniprot/RPA2_HUMAN RPA2_HUMAN] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.<ref>PMID:16809778</ref>
 == References ==
 <references/>