8dfz: Difference between revisions
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==NMR shows why a small chemical change almost abolishes the antimicrobial activity of GccF== | |||
<StructureSection load='8dfz' size='340' side='right'caption='[[8dfz]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8dfz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactiplantibacillus_plantarum Lactiplantibacillus plantarum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DFZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EW6:alpha-methyl-L-serine'>EW6</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
[[Category: Edwards | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dfz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dfz OCA], [https://pdbe.org/8dfz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dfz RCSB], [https://www.ebi.ac.uk/pdbsum/8dfz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dfz ProSAT]</span></td></tr> | ||
[[Category: Harjes | </table> | ||
[[Category: Norris | == Function == | ||
[https://www.uniprot.org/uniprot/GCCF_LACPN GCCF_LACPN] Has antibacterial activity against L.plantarum ATCC 8014. In purified form, the activity is bacteriostatic (IC(50)=2 nM) rather than bactericidal.<ref>PMID:21251913</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Lactiplantibacillus plantarum]] | |||
[[Category: Large Structures]] | |||
[[Category: Edwards PJB]] | |||
[[Category: Harjes E]] | |||
[[Category: Norris G]] | |||
Latest revision as of 05:41, 5 July 2023
NMR shows why a small chemical change almost abolishes the antimicrobial activity of GccF
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