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'''Unreleased structure'''


The entry 8atg is ON HOLD  until Paper Publication
==Pentameric ligand-gated ion channel GLIC with bound lipids==
 
<StructureSection load='8atg' size='340' side='right'caption='[[8atg]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
Authors: Bergh, C., Rovsnik, U., Howard, R.J., Lindahl, E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8atg]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus Gloeobacter violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ATG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ATG FirstGlance]. <br>
Description: Pentameric ligand-gated ion channel GLIC with bound lipids
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr>
[[Category: Howard, R.J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8atg OCA], [https://pdbe.org/8atg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8atg RCSB], [https://www.ebi.ac.uk/pdbsum/8atg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8atg ProSAT]</span></td></tr>
[[Category: Bergh, C]]
</table>
[[Category: Lindahl, E]]
== Function ==
[[Category: Rovsnik, U]]
[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gloeobacter violaceus]]
[[Category: Large Structures]]
[[Category: Bergh C]]
[[Category: Howard RJ]]
[[Category: Lindahl E]]
[[Category: Rovsnik U]]
Retrieved from "https://proteopedia.org/8atg"