1irp: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 1: Line 1:
[[Image:1irp.gif|left|200px]]
{{Seed}}
[[Image:1irp.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1irp|  PDB=1irp  |  SCENE=  }}  
{{STRUCTURE_1irp|  PDB=1irp  |  SCENE=  }}  


'''SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN'''
===SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN===




==Overview==
<!--  
Interleukin-1 receptor antagonist protein (IRAP) is a naturally occurring inhibitor of the interleukin-1 receptor. In contrast to IL-1 beta, IRAP binds to the IL-1 receptor but does not elicit a physiological response. We have determined the solution structure of IRAP using NMR spectroscopy. While the overall topology of the two 153-residue proteins is quite similar, functionally critical differences exist concerning the residues of the linear amino acid sequence that constitute structurally homologous regions in the two proteins. Structurally homologous residues important for IL-1 receptor binding are conserved between IRAP and IL-1 beta. By contrast, structurally homologous residues critical for receptor activation are not conserved between the two proteins.
The line below this paragraph, {{ABSTRACT_PUBMED_8045306}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 8045306 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_8045306}}


==About this Structure==
==About this Structure==
1IRP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IRP OCA].  
1IRP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IRP OCA].  


==Reference==
==Reference==
Line 26: Line 30:
[[Category: Strakalaitis, N A.]]
[[Category: Strakalaitis, N A.]]
[[Category: Cytokine]]
[[Category: Cytokine]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:19:59 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 13:53:08 2008''
Retrieved from "https://proteopedia.org/1irp"