4gmk: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
Line 4: Line 4:
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gmk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ligilactobacillus_salivarius_UCC118 Ligilactobacillus salivarius UCC118]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GMK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gmk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ligilactobacillus_salivarius_UCC118 Ligilactobacillus salivarius UCC118]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GMK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmk OCA], [https://pdbe.org/4gmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gmk RCSB], [https://www.ebi.ac.uk/pdbsum/4gmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gmk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmk OCA], [https://pdbe.org/4gmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gmk RCSB], [https://www.ebi.ac.uk/pdbsum/4gmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gmk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[https://www.uniprot.org/uniprot/Q1WR87_LIGS1 Q1WR87_LIGS1] Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.[HAMAP-Rule:MF_00170]
[https://www.uniprot.org/uniprot/Q1WR87_LIGS1 Q1WR87_LIGS1] Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.[HAMAP-Rule:MF_00170]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC188 has been determined at 1.72 A resolution. The structure was solved by molecular replacement, which identified the functional homodimer in the asymmetric unit. Despite only showing 57% sequence identity to its closest homologue, the structure adopted the typical alpha and beta D-ribose 5-phosphate isomerase fold. Comparison to other related structures revealed high homology in the active site, allowing a model of the substrate-bound protein to be proposed. The determination of the structure was expedited by the use of in situ crystallization-plate screening on beamline I04-1 at Diamond Light Source to identify well diffracting protein crystals prior to routine cryocrystallography.
Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118.,Lobley CM, Aller P, Douangamath A, Reddivari Y, Bumann M, Bird LE, Nettleship JE, Brandao-Neto J, Owens RJ, O'Toole PW, Walsh MA Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1427-33., doi: 10.1107/S174430911204273X. Epub 2012 Nov 14. PMID:23192019<ref>PMID:23192019</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4gmk" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Ribose-5-phosphate isomerase 3D structures|Ribose-5-phosphate isomerase 3D structures]]
*[[Ribose-5-phosphate isomerase 3D structures|Ribose-5-phosphate isomerase 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 11:32, 1 March 2024

Crystal Structure of Ribose 5-Phosphate Isomerase from the Probiotic Bacterium Lactobacillus salivarius UCC118

4gmk, resolution 1.72Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=4gmk&oldid=4073825"