Sandbox Q123: Difference between revisions

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<StructureSection load='3m7p' size='350' side='right' scene='43/430871/Cv/2' caption='Human glycosylated fibronectin gelatin-binding domain complex with PEG400, dodecaethylene glycol and Zn+2 ions (grey) (PDB code [[3m7p]]) '>
<StructureSection load='3m7p' size='350' side='right' scene='43/430871/Cv/2' caption='Human glycosylated fibronectin gelatin-binding domain complex with PEG400, dodecaethylene glycol and Zn+2 ions (grey) (PDB code [[3m7p]]) '>
== Structural insights ==
<scene name='43/430871/Cv/3'>Fn is a dimer of homologous monomers</scene> linked by S-S bond.  Each monomer contains 3 types of modules: FnI, FnII and FnIII.  Each module contains several numbered protein binding domains, i.e., FnI<sub>6</sub>-FnII<sub>1-2</sub>-FnI<sub>7-9</sub> is the gelatin binding domain (GBD).
This is a test, <scene name='93/932569/297-307_space_fill/1'>Space Fill 297-307</scene>, of FN.
== 3D Structures of Fibronectin ==
[[Fibronectin 3D structures]]
</StructureSection>


== Function ==
== Function ==
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Overexpression of Fn1 is associated with lung cancer<ref>PMID:16397245</ref>.
Overexpression of Fn1 is associated with lung cancer<ref>PMID:16397245</ref>.
== Structural insights ==
<scene name='43/430871/Cv/3'>Fn is a dimer of homologous monomers</scene> linked by S-S bond.  Each monomer contains 3 types of modules: FnI, FnII and FnIII.  Each module contains several numbered protein binding domains, i.e., FnI<sub>6</sub>-FnII<sub>1-2</sub>-FnI<sub>7-9</sub> is the gelatin binding domain (GBD).
This is a test, <scene name='93/932569/297-307_space_fill/1'>Space Fill 297-307</scene>, of FN.
== 3D Structures of Fibronectin ==
[[Fibronectin 3D structures]]
</StructureSection>


== References ==
== References ==