Sandbox Q123: Difference between revisions
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Qinlin Zeng (talk | contribs) No edit summary |
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<StructureSection load='3m7p' size='350' side='right' scene='43/430871/Cv/2' caption='Human glycosylated fibronectin gelatin-binding domain complex with PEG400, dodecaethylene glycol and Zn+2 ions (grey) (PDB code [[3m7p]]) '> | <StructureSection load='3m7p' size='350' side='right' scene='43/430871/Cv/2' caption='Human glycosylated fibronectin gelatin-binding domain complex with PEG400, dodecaethylene glycol and Zn+2 ions (grey) (PDB code [[3m7p]]) '> | ||
== Structural insights == | |||
<scene name='43/430871/Cv/3'>Fn is a dimer of homologous monomers</scene> linked by S-S bond. Each monomer contains 3 types of modules: FnI, FnII and FnIII. Each module contains several numbered protein binding domains, i.e., FnI<sub>6</sub>-FnII<sub>1-2</sub>-FnI<sub>7-9</sub> is the gelatin binding domain (GBD). | |||
This is a test, <scene name='93/932569/297-307_space_fill/1'>Space Fill 297-307</scene>, of FN. | |||
== 3D Structures of Fibronectin == | |||
[[Fibronectin 3D structures]] | |||
</StructureSection> | |||
== Function == | == Function == | ||
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Overexpression of Fn1 is associated with lung cancer<ref>PMID:16397245</ref>. | Overexpression of Fn1 is associated with lung cancer<ref>PMID:16397245</ref>. | ||
== References == | == References == | ||