8b3c: Difference between revisions
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==chalcone synthase from Hordeum vulgare complexed with malonyl-CoA== | |||
<StructureSection load='8b3c' size='340' side='right'caption='[[8b3c]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8b3c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B3C FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ERD:(2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE'>ERD</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b3c OCA], [https://pdbe.org/8b3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b3c RCSB], [https://www.ebi.ac.uk/pdbsum/8b3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b3c ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CHS2_HORVU CHS2_HORVU] The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. Substrate preference is feruloyl-CoA = caffeoyl-CoA >> cinnamoyl-CoA. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hordeum vulgare]] | |||
[[Category: Large Structures]] | |||
[[Category: Groves MR]] | |||
[[Category: Zhang L]] | |||
Revision as of 06:52, 27 September 2023
chalcone synthase from Hordeum vulgare complexed with malonyl-CoA
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