Biological Unit: Difference between revisions

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Eric Martz (talk | contribs)
ConfirmAccount, Editor, Print3D, Tester, journal, Administrators
30,118 edits
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===Software: Protein Interfaces, Surfaces and Assemblies Server (PISA)===
===Software: Protein Interfaces, Surfaces and Assemblies Server (PISA)===


The [http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html Protein Interfaces, Surfaces and Assemblies Server] (PISA) at the European Bioinformatics Institute uses improved methods to predict the biological unit or probable quaternary assembly, compared to its predecessor PQS (see next section). These servers examine the contacts that occur in macromolecular crystals used in [[X-ray crystallography]]. They attempt to discriminate between [[crystal contacts]] (artifacts of crystallization) and contacts between chains that have co-evolved to maintain specific oligomeric binding.
The [http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html Protein Interfaces, Surfaces and Assemblies Server] (PISA) at the European Bioinformatics Institute uses improved methods to predict the biological unit or probable quaternary assembly, compared to its predecessor PQS. It examines the contacts that occur in macromolecular crystals used in [[X-ray crystallography]]. It attempts to discriminate between [[crystal contacts]] (artifacts of crystallization) and contacts between chains that have co-evolved to maintain specific oligomeric binding.


===Software: Evolutionary Protein-Protein Interface Classifier (EPPIC)===
===Software: Evolutionary Protein-Protein Interface Classifier (EPPIC)===
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