Biological Unit: Difference between revisions
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Truncated proteins may form oligomers that are impossible in the native protein. For example, [[1bk5]] (karyopherin alpha) is a truncated part of the natural chain, and forms a dimer that would be prevented by the full-length chain. Dimerization is dependent upon Y397. Mutation Y397D prevents this artifactual dimerization, leading to the monomer [[1ee5]]. | Truncated proteins may form oligomers that are impossible in the native protein. For example, [[1bk5]] (karyopherin alpha) is a truncated part of the natural chain, and forms a dimer that would be prevented by the full-length chain. Dimerization is dependent upon Y397. Mutation Y397D prevents this artifactual dimerization, leading to the monomer [[1ee5]]. | ||
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==Visualizing the Biological Unit== | ==Visualizing the Biological Unit== | ||
===FirstGlance in Jmol=== | ===FirstGlance in Jmol=== | ||
FirstGlance in Jmol makes it quick and easy to see the biological unit. The initial display in FirstGlance is automatically "biomolecule 1" from REMARK 350. When it is very large, it will be automatically [http://firstglance.jmol.org/notes.htm#simplification simplified to alpha carbon atoms (or a subset thereof)] automatically by FirstGlance. | FirstGlance in Jmol makes it quick and easy to see the biological unit. The initial display in FirstGlance is automatically "biomolecule 1" from REMARK 350. When it is very large, it will be automatically [http://firstglance.jmol.org/notes.htm#simplification simplified to alpha carbon atoms (or a subset thereof)] automatically by FirstGlance. | ||
