Sandbox Reserved 1735: Difference between revisions
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== Structural Highlights of HIV-1 | == Structural Highlights of HIV-1 protease== | ||
==Structural Highlights of HIV-2 | ==Structural Highlights of HIV-2 protease== | ||
== HIV-1 | == HIV-1 Protease in Humans== | ||
HIV-1 is more transmissible than HIV-2 and is more likely to lead to AIDS in a patient. “HIV-1 protease (PR) is a virus-encoded proteolytic enzyme that is initially systemized as part of the GagPol polyprotein” (Huang et. al, 2013). HIV-1 protease belongs to Clan AA, family A2 of the aspartic proteases. Aspartic proteases are the smallest group of proteases found in humans (Huang et. al, 2013). | HIV-1 is more transmissible than HIV-2 and is more likely to lead to AIDS in a patient. “HIV-1 protease (PR) is a virus-encoded proteolytic enzyme that is initially systemized as part of the GagPol polyprotein” (Huang et. al, 2013). HIV-1 protease belongs to Clan AA, family A2 of the aspartic proteases. Aspartic proteases are the smallest group of proteases found in humans (Huang et. al, 2013). | ||
==HIV-2 | ==HIV-2 Protease in Humans== | ||
==The role of CD4+ T-cell== | ==The role of CD4+ T-cell== | ||
| Line 29: | Line 29: | ||
==HIV Prevention== | ==HIV Prevention== | ||
== References == | == References == | ||
Revision as of 19:57, 14 November 2022
| This Sandbox is Reserved from August 30, 2022 through May 31, 2023 for use in the course Biochemistry I taught by Kimberly Lane at the Radford University, Radford, VA, USA. This reservation includes Sandbox Reserved 1730 through Sandbox Reserved 1749. |
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HIV-1 Protease
<StructureSection load='3hvp' size='340' side='right' caption='Caption for this structure' scene=> This is a default text for your page '. Click above on edit this page' to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Introduction
Structural Highlights of HIV-1 protease
Structural Highlights of HIV-2 protease
HIV-1 Protease in Humans
HIV-1 is more transmissible than HIV-2 and is more likely to lead to AIDS in a patient. “HIV-1 protease (PR) is a virus-encoded proteolytic enzyme that is initially systemized as part of the GagPol polyprotein” (Huang et. al, 2013). HIV-1 protease belongs to Clan AA, family A2 of the aspartic proteases. Aspartic proteases are the smallest group of proteases found in humans (Huang et. al, 2013).
HIV-2 Protease in Humans
The role of CD4+ T-cell
Protease Inhibitors for HIV-1 Treatment
Protease Inhibitors for HIV-2 Treatment
Evolution's Role
HIV Prevention
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:https://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
